Causes, Symptoms of Non-CF Bronchiectasis Have Changed in Children, Study Suggests

Causes, Symptoms of Non-CF Bronchiectasis Have Changed in Children, Study Suggests
Children diagnosed with non-cystic fibrosis bronchiectasis since 2002 have better lung function at diagnosis, distinct disease causes, and higher frequency of sputum infections, compared to children followed in the same center years earlier, a Turkish study found. The study, "Changing clinical characteristics of non-cystic fibrosis bronchiectasis in children," was published in the journal BMC Pulmonary Medicine. Bronchiectasis often occurs secondary to another medical condition such as cystic fibrosis, pulmonary disorders, respiratory tract infections, and allergies. But with increases in vaccination programs that prevent pulmonary infections and increased access to healthcare, the causes leading to bronchiectasis appear to have changed in the past couple of decades. Researchers at the Marmara University, School of Medicine, Turkey, set out to assess causes and other disease features in children with non-cystic fibrosis bronchiectasis followed at their clinic from 2002 to 2019. For comparison, they examined a previously described group of children followed in the same clinic from 1987 to 2001. The most recent group included 104 children, a nearly equal mix of boys and girls, with a median age of 8 years. They had been diagnosed at a median age of 7, presenting
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