Low Bacterial Diversity in Lungs Tied to Damaging Enzyme in Bronchiectasis

Low Bacterial Diversity in Lungs Tied to Damaging Enzyme in Bronchiectasis
A low diversity of bacterial species in the lungs of adults with bronchiectasis is linked with higher levels of an enzyme called active neutrophil elastase (NE), as well as greater disease severity and worse lung function, a study discovered.  High levels of neutrophil elastase were specifically related to infections by Pseudomonas aeruginosa The study, “Sputum Neutrophil Elastase associates with microbiota and P. aeruginosa in bronchiectasis,” was published in the journal European Respiratory Journal Airway inflammation caused by immune cells called neutrophils is thought to be one of the major drivers of bronchiectasis. In fact, up to 80% of bronchiectasis patients experience inflammation related to neutrophils.  These cells s
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