There is no cure for bronchiectasis because the damage to the airways can’t be reversed, but its symptoms and lung infections can be treated. The goal is to treat the underlying conditions and lung infections, to remove mucus from the lungs, and to prevent further complications.

Medicines prescribed for bronchiectasis treatment

Some of the medicines or treatments usually prescribed for bronchiectasis are antibiotics, bronchodilators, expectorants, and mucus-thinning drugs. In most cases, treatment involves a combination of medication and the use of devices and exercises to help clear the airways.

Infection treatment

Antibiotics are the most common treatment for lung infections, which can be common in people with bronchiectasis. Some people take continuous antibiotics because they get a lot of infections. Antibiotics may be taken orally, or in case of more difficult to treat infections, they may be given intravenously.

Oral antibiotics currently in use to treat acute exacerbations of bronchiectasis in adults are amoxicillin, co-amoxiclav, flucloxacillin, rifampicin, fucidin,  and ciprofloxacin.

Intravenous antibiotics may be required in severe cases, or where oral use fails to treat an acute exacerbation. IV antibiotics currently in use for such cases are benzylpenicillin, cefuroxime, ceftriaxone  vancomycin, ceftazidime and cefuroxime.

Long-term antibiotics are used in people with bronchiectasis to improve disease symptoms, decrease exacerbation rates, and improve quality of life. These include amoxicillin, flucloxacillin and trimethoprim.

The choice of the adequate antibiotic will depend on the specific bacteria that is causing the infection.

Bronchodilators for bronchiectasis

Bronchodilators relax the muscles around the airways. The majority of the bronchodilators are inhaled medications, taken using an inhaler or a nebulizer. They help to open the airways so breathing is easier.

The bronchodilators commonly used for bronchiectasis treatment include short-acting bronchodilators, such as albuterol and levalbuterol, and long-acting bronchodilators, such as formoterol, tiotropium and salmeterol.

Short-acting bronchodilators are used as a rescue medication when there is a need for quick relief of shortness of breath, and long-acting bronchodilators are used regularly to control bronchiectasis symptoms.

Expectorants and mucus-thinning medicines for bronchiectasis

Expectorants and mucus-thinning medicines help to clear mucus. Both work to loosen the mucus in the lungs,  making it easier to cough out of the airways. Expectorants or mucus clearance agents, include hypertonic saline and inhaled mannitol, that keeps the airways hydrated and enhance clearance and mucolytics, such as bromhexineN-acetylcysteineerdosteine and fudosteine and dornase alfa.

Expectorants may be combined with decongestants.

Other bronchiectasis treatments

Other bronchiectasis treatments include hydration, which turns the mucus thinner and easier to cough up; chest physical therapy (chest clapping or percussion) done by a therapist or trained family member, using their hands or an external device, to loosen mucus and help move it out of the lungs, or with an external device, like therapy vest that uses high-frequency air waves; oxygen therapy to raise low blood-oxygen levels; and corticosteroids to treat airway inflammation.

Surgery may be considered if other treatments do not help and only one part of the airway is affected, if symptoms aren’t responding to other treatment or if major bleeding takes place.

 

Bronchiectasis News Today is strictly a news and information website about the disease. It does not provide medical advice, diagnosis or treatment. This content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or another qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.

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